Nuclear Medicine

Our specialist

Dr.-Shashank-Shekhar-Singh-doctor-of-Globe-Healthcare

Dr. Shashank Shekhar Singh

Senior Consultant | Nuclear Medicine

MBBS, DNB (Nuclear Medicine)

Dr. Shashank Shekhar Singh specializes in PET/CT, Gamma camera procedures, and radionuclide therapy with more than nine years of experience. Formerly at PGIMER Chandigarh, AIIMS Rishikesh, and Apollo Lucknow.

Introduction to Nuclear Medicine

Nuclear Medicine is the branch of medicine that utilizes minimal quantities of disease-targeted radioactive probes called radiotracers for evaluating the function of various organs, diagnosing different cancers, and treating diseases. It assesses the functionality of tissue at the molecular and cellular level using special scanners like PET/CT and Gamma Camera. The main advantage of nuclear medicine lies in the early detection of different diseases at the molecular level before anatomical changes imaged by CT or MRI set in. Additionally, the physiological and metabolic information provided by these specific radiotracers enables us to assess early response to treatments which often alters the treatment strategy.

Therapeutic nuclear medicine uses very targeted alpha and beta particle emitting radioisotopes to specifically destroy diseased cells. They are used in the treatment of various cancers and non-cancerous conditions with minimal side effects.

At Globe Healthcare, we have a state-of-the-art Nuclear Medicine Department, complete with Digital PET-CT (first in the state of Uttar Pradesh), Dual head Gamma Camera and radionuclide therapy unit.

Nuclear medicine procedures are safe, easy to perform, non-invasive and impart minimal radiation. With digital PET-CT, we are further able to perform the scans at half the radiation dose and scan time for benefit of our patients.
Radionuclide therapies use very specific alpha and beta emitting radionuclides which specifically destroys the diseased cells without harming the normal tissue making them very safe and effective.

Positron Emission Tomography (PET)

Positron Emission Tomography (PET) is cutting-edge technology in the armamentarium of diagnostic nuclear medicine, particularly in cancer imaging. This modality uses the administration of tumor-specific ‘positron isotopes’, which emit annihilation photons imaged by PET/CT scanners. The most commonly used radiotracer is 18F-FDG which is a radioactive analog of glucose. Most cancer cells are glucose hungry and utilize more glucose compared to the normal tissue. Thus, FDG helps us to study the metabolic behavior of cancer cells earlier and more accurately than the conventional radiological modalities like CT scans and MRI.

PET scan combined with a whole-body diagnostic CT scan often serves the purpose of a “one-stop shop” for the cancer work-up.

There are many more new radiotracers; some of them are already in clinical use, and many others are in the pipeline at various stages of clinical trials, which can give us a better understanding of many disease processes.

  • 18F-FDG: Most versatile radiotracer which tells about glucose metabolism in tumors/inflammation.
  • Lymphoma, lung cancer, breast, large and small bowel, Paraneoplastic, multiple myeloma, melanoma
  • 68Ga/18F-PSMA: Prostate cancer
  • 68Ga-DOTATATE: Neuroendocrine tumors, paraganglioma, pheochromocytoma, opsoclonus myoclonus syndromes, meningiomas, Tumour induced Osteomalacia, Paraneoplastic, medullary thyroid cancer.
  • Tumor microenvironment.
  • 68Ga-exendin: for insulinoma
  • 18F-DOPA: Neuroendocrine tumors, Medullary thyroid cancer
  • 68Ga-PENTIXOFOR: multiple myeloma, lung cancer, brain tumors

Gamma camera procedures

Gamma camera helps to image different organs using various 99mTc labeled radiotracers. Some of the commonly used gamma camera procedures are:

  • Renal scans: DTPA, DMSA, EC
  • Stress Myocardial perfusion Imaging (stress MPI) or Stress Thallium
  • Myocardial Viability scan
  • Thyroid scan
  • Parathyroid scan
  • Bone scan
  • Three-phase bone scan for bone infections
  • Brain scans: Tro-DAT for movement disorders, ECD/ HMPAO for brain perfusion
  • HIDA scan for hepatobiliary system
  • Lymphoscintigraphy
  • MUGA scan
  • Meckel’s scan
  • G.I Bleed scintigraphy

Radionuclide therapies

Nuclear medicine therapies use specific radionuclides, which emit Beta particles (131-Iodine, 177-Lutetium,153-Samarium) or Alpha particles (225-Actinium) to treat different diseases.

Commonly used radionuclides are:

  • Radioactive Iodine (131-I): Graves’ disease, Toxic adenoma, Toxic MNG, Thyroid cancer
  • 177-Lu/225-Ac DOTATATE: For Neuroendocrine Tumours
  • 177-Lu/225-Ac PSMA: For Prostate cancer
  • Radio synovectomy: 177-Lu colloid
  • Trans arterial radioembolization (TARE): Hepatocellular carcinoma, liver metastases
  • Bone pain palliation: 177-Lu EDTMP, 153-Samarium

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Lucknow

Dr. Mohd. Suhaib

Senior Consultant Radiation Oncology

MBBS, MD Radiation Oncology

He Specialises in treating cancer with advanced Radiation techniques, SRS/SRT/SBRT, and radiation in moving objects like lungs and liver.

He has more than eight years of Clinical Experience.
He was formerly at SGPGI, Lucknow & Apollo, Lucknow.

Dr. Deepak Kumar Agarwal

Founder, Managing Director & Chief Gastroenterlogogist Globe Medicare & President Gastrocare Medical Research Foundation

MBBS and M D (Internal Medicine)
DM (Gastroenterology)

Dr. Deepak Kumar Agarwal underwent his MBBS and M D (Internal Medicine) from prestigious King George College, Lucknow, U.P. He was awarded Gold Medal for his outstanding performance as an MD student (best Student, best resident, and best researcher). He joined Sanjay Gandhi Post Graduate Institute, Lucknow, U.P, to complete his DM (Gastroenterology), and subsequently continued his academic carrier at Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, by undergoing advanced training programs and acquiring newer endoscopic skills.

At SGPGIMS, he pursued his academic interest in the hepato-biliary-pancreatic area and developed it as a subspecialty. Apart from starting a dedicated clinic, all interventional procedures, including Diagnostic and therapeutic ERCP, were also evolved. For the first time in India (1990) – a) Endoscopic Ultra Sonography assessment of hepato-biliary-pancreatic areas (EUS), b) Biliary and pancreatic Lithotripsy and Diagnostic tools for predicting Gallstone composition in vivo were introduced at SGPIMS. He was instrumental in developing all these procedures. His clinical research work resulted in around 50 publications, the majority of them in International reputed journals with high impact factors. He took the department to new heights at the national and international levels. During his tenure, he bagged almost all awards at national and state-level conferences in the hepato-biliary-pancreatic area.

For his academic contribution, he was elected as President of the U.P State Chapter of the Indian Society of Gastroenterology and delivered the presidential oration “Past, Present and Future of Gastroenterology in Uttar Pradesh.” He, for the first time, brought the concept of sub-specialty in Gastroenterology. His work on Chronic Liver Disease, particularly Alcohol-induced, has encouraged newer treatment options for this very common problem. To serve the people of his state of Uttar Pradesh, he started the first Gastroenterology center in the state in 2006, providing all the facilities, both basic and advanced (Fibroscan, Endoscopic Ultrasound, Endoscopy & ERCP, Capsule Endoscopy, etc.) under one roof, thus helping patients suffering from various gastrointestinal & hepatobiliary disorders. Over 25 years of practice, he has treated half a million patients and trained many budding gastroenterologists. GASTROCARE MEDICAL RESEARCH FOUNDATION [CHARITABLE SOCIETY] started nine years back; under his able guidance, he has organized free medical health camps in Lucknow & adjoining rural areas. Regular CME programs were conducted by eminent expert national faculty, being attended by more than 600 delegates every year from all over UP and adjoining states. These Continuous Medical Education (CME) programs highlight the propagation of knowledge to the younger gastroenterologist, physicians, and surgeons from all over Uttar Pradesh. These training programs have not only benefited doctors but also have helped in better treatment of patients from both urban and rural areas. Uttar Pradesh government keeping his these contributions in the field of medicine, awarded him with the highest civilian honor of the state – the Yash Bharti Award 2016. For his continuous contribution towards the advancement of medical science (Gastro medicine), he was recently awarded Fellowship of Royal College of Physicians of Edinburgh, United Kingdom, 2017. 

Dr. Dhiraj Singh

Consultant, Nephrology & Renal Transplant

MBBS, MD (KGMU, Lucknow), DM Nephrology (AIIMS, New Delhi)
Member of ISN and ISOT

Dr. Shashank Shekhar Singh

Consultant Nuclear Medicine

MBBS, DNB Nuclear Medicine.

Dr. Shashank Shekhar Singh specializes in PET/CT, Gamma camera procedures, and radionuclide therapy with more than nine years of experience. Formerly at PGIMER Chandigarh, AIIMS Rishikesh, and Apollo Lucknow.

Dr. Resham Srivastava

Senior Consultant Radiation Oncology

MBBS, MD, Radiation Oncology (SGPGIMS), DNB Radiation Oncology.
Ex-Registrar (KGMU)
Ex-Faculty Tata Memorial Hospital Varanasi.

Dr. Resham Srivastava has more than 11 years of experience in the field of oncology. She did her MD in Radiation Oncology from SGPGI. After then, she worked as a senior registrar at SGPGI and KGMU. Before to Globe Healthcare, she worked as Assistant Professor of Radiation Oncology at Tata Memorial Hospital, Varanasi. She is specialized and trained in updated technology in radiation, VMAT, SBRT, IGRT, DIBH (motion management), and brachytherapy.

Dr. Kamlesh Verma

Director Surgical Oncology

MBBS, MS, M.Ch. (Surgical Oncology) – TATA Memorial Centre Mumbai, India.

Dr. Kamlesh Verma is a highly skilled surgical oncologist with 13 years of experience and a particular interest in minimally invasive cancer surgery. Expert in laparoscopy, video-assisted thoracoscopic surgery (VATS), and robotic surgery for smooth & pain-free recovery from Cancer.

He is also trained in Hyperthermic Intraperitoneal chemotherapy (HIPEC) and Pressurised Intraperitoneal Aerosol Chemotherapy (PIPAC).

He has fellowships in Thoracic Oncology and Colorectal Surgery.

Dr. Abhishek Kumar Singh

Senior Consultant Medical & Hemato Oncology at Globe Cancer Center, Lucknow

MBBS, DNB (Medicine), DNB (Medical Oncology)
Perceptorship GI Oncology, NCCS, Singapore
Ex - Assistant Professor Medical Oncology TATA Memorial Hospital (HBCH/MPMMCC)
Ex Director, Medical Oncology, Chandan Hospital, Lucknow

Specialised in all type of cancer management, both solid and liquid (Blood) malignancy, cancer pain management and palliative care.
More than 9 years of experience in cancer treatment by Chemotherapy, Immunotherapy, Targeted therapy, Hormone therapy.